Functional Characterization of D9, a Novel Deazaneplanocin A (DZNep) Analog, in Targeting Acute Myeloid Leukemia (AML)

Aberrant epigenetic events contribute to tumorigenesis of all human cancers. Significant efforts are underway in developing new generation of epigenetic cancer therapeutics. Although clinical trials for agents targeting DNA hypermethylation and histone deacetylation have yielded promising results, d...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jiang, Xia, Lim, Cheryl Zi Hui, Li, Zhimei, Lee, Puay Leng, Yatim, Siti Maryam J. M., Guan, Peiyong, Li, Juntao, Zhou, Jianbiao, Pan, Jingxuan, Chng, Wee-Joo, Chai, Christina L. L., Yu, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415792/
https://ncbi.nlm.nih.gov/pubmed/25928216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122983
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