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Aberrant RNA splicing and mutations in spliceosome complex in acute myeloid leukemia
The spliceosome, the cellular splicing machinery, regulates RNA splicing of messenger RNA precursors (pre-mRNAs) into maturation of protein coding RNAs. Recurrent mutations and copy number changes in genes encoding spliceosomal proteins and splicing regulatory factors have tumor promoting or suppres...
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| Vydáno v: | Stem Cell Investig |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
AME Publishing Company
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5313292/ https://ncbi.nlm.nih.gov/pubmed/28217708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/sci.2017.01.06 |
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