Pharmacokinetic–pharmacodynamic modelling of intravenous and oral topiramate and its effect on phonemic fluency in adult healthy volunteers

AIMS: The aim was to develop a quantitative approach that characterizes the magnitude of and variability in phonemic generative fluency scores as measured by the Controlled Oral Word Association (COWA) test in healthy volunteers after administration of an oral and a novel intravenous (IV) formulatio...

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Dades bibliogràfiques
Publicat a:Br J Clin Pharmacol
Autors principals: Ahmed, Ghada F, Marino, Susan E, Brundage, Richard C, Pakhomov, Serguei V S, Leppik, Ilo E, Cloyd, James C, Clark, Annie, Birnbaum, Angela K
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2015
Matèries:
Pharmacokinetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415718/
https://ncbi.nlm.nih.gov/pubmed/25403343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12556
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