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USL255 extended-release topiramate: Dose-proportional pharmacokinetics and tolerability in healthy volunteers
OBJECTIVE: Evaluate the pharmacokinetics (PK), safety, and tolerability of single doses of once-daily USL255, Qudexy XR (topiramate) extended-release capsules, over a wide dosing range. METHODS: Two single-dose, phase I studies in healthy adults were used to evaluate the PK profile and maximum toler...
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| Publicado no: | Epilepsia |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4283972/ https://ncbi.nlm.nih.gov/pubmed/24861853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.12654 |
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