USL255 extended-release topiramate: Dose-proportional pharmacokinetics and tolerability in healthy volunteers

OBJECTIVE: Evaluate the pharmacokinetics (PK), safety, and tolerability of single doses of once-daily USL255, Qudexy XR (topiramate) extended-release capsules, over a wide dosing range. METHODS: Two single-dose, phase I studies in healthy adults were used to evaluate the PK profile and maximum toler...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Epilepsia
Egile Nagusiak: Clark, Annie M, Halvorsen, Mark B, Braun, Tricia L, Johnson, Krista M, Cloyd, James C
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BlackWell Publishing Ltd 2014
Gaiak:
Full-Length Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283972/
https://ncbi.nlm.nih.gov/pubmed/24861853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.12654
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