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Intravenous Topiramate: Pharmacokinetics in Dogs with Naturally Occurring Epilepsy

RATIONALE: Barriers to developing treatments for human status epilepticus include the inadequacy of experimental animal models. In contrast, naturally occurring canine epilepsy is similar to the human condition and can serve as a platform to translate research from rodents to humans. The objectives...

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Veröffentlicht in:Front Vet Sci
Hauptverfasser: Vuu, Irene, Coles, Lisa D., Maglalang, Patricia, Leppik, Ilo E., Worrell, Greg, Crepeau, Daniel, Mishra, Usha, Cloyd, James C., Patterson, Edward E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5136567/
https://ncbi.nlm.nih.gov/pubmed/27995128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fvets.2016.00107
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