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Traceless semisynthesis of a set of histone 3 species bearing specific lysine methylation marks

Considerable mechanistic insight into the function of histone posttranslational modifications and the enzymes that install and remove them derives from in vitro experiments with modified histones, often embedded in nucleosomes. We report the first semisyntheses of native-like histone 3 (H3) bearing...

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Pubblicato in:Chembiochem
Autori principali: Chen, Zhonglei, Grzybowski, Adrian T., Ruthenburg, Alexander J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415702/
https://ncbi.nlm.nih.gov/pubmed/25155436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201402313
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