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Mechanism of histone methylation catalyzed by protein lysine methyltransferase SET7/9 and origin of product specificity

Methylation of certain lysine residues in the N-terminal tails of core histone proteins in nucleosome is of fundamental importance in the regulation of chromatin structure and gene expression. Such histone modification is catalyzed by protein lysine methyltransferases (PKMTs). PKMTs contain a conser...

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Detalhes bibliográficos
Main Authors: Guo, Hao-Bo, Guo, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885582/
https://ncbi.nlm.nih.gov/pubmed/17517655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702981104
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