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Mechanism of histone methylation catalyzed by protein lysine methyltransferase SET7/9 and origin of product specificity

Methylation of certain lysine residues in the N-terminal tails of core histone proteins in nucleosome is of fundamental importance in the regulation of chromatin structure and gene expression. Such histone modification is catalyzed by protein lysine methyltransferases (PKMTs). PKMTs contain a conser...

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Autores principales: Guo, Hao-Bo, Guo, Hong
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885582/
https://ncbi.nlm.nih.gov/pubmed/17517655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702981104
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