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Traceless semisynthesis of a set of histone 3 species bearing specific lysine methylation marks

Considerable mechanistic insight into the function of histone posttranslational modifications and the enzymes that install and remove them derives from in vitro experiments with modified histones, often embedded in nucleosomes. We report the first semisyntheses of native-like histone 3 (H3) bearing...

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Vydáno v:Chembiochem
Hlavní autoři: Chen, Zhonglei, Grzybowski, Adrian T., Ruthenburg, Alexander J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415702/
https://ncbi.nlm.nih.gov/pubmed/25155436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201402313
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