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Incubation of ovine scrapie with environmental matrix results in biological and biochemical changes of PrP(Sc) over time
Ovine scrapie can be transmitted via environmental reservoirs. A pool of ovine scrapie isolates were incubated on soil for one day or thirteen months and eluted prion was used to challenge tg338 mice transgenic for ovine PrP. After one-day incubation on soil, two PrP(Sc) phenotypes were present: G(3...
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| Udgivet i: | Vet Res |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4415298/ https://ncbi.nlm.nih.gov/pubmed/25928902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13567-015-0179-y |
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