Lymph node fibroblastic reticular cell transplants show robust therapeutic efficacy in high-mortality murine sepsis

Sepsis is an aggressive inflammatory syndrome and a global health burden estimated to kill 7.3 million people annually. Single-target molecular therapies have not addressed the multiple disease pathways triggered by septic injury. Cell therapies might offer a broader set of mechanisms of action that...

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Bibliographic Details
Published in:Sci Transl Med
Main Authors: Fletcher, Anne L., Elman, Jessica S., Astarita, Jillian, Murray, Ryan, Saeidi, Nima, D’Rozario, Joshua, Knoblich, Konstantin, Brown, Flavian D., Schildberg, Frank A., Nieves, Janice M., Heng, Tracy S. P., Boyd, Richard L., Turley, Shannon J., Parekkadan, Biju
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415170/
https://ncbi.nlm.nih.gov/pubmed/25122637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3009377
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