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A2aR antagonists: Next generation checkpoint blockade for cancer immunotherapy

The last several years have witnessed exciting progress in the development of immunotherapy for the treatment of cancer. This has been due in great part to the development of so-called checkpoint blockade. That is, antibodies that block inhibitory receptors such as CTLA-4 and PD-1 and thus unleash a...

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Leone, Robert D., Lo, Ying-Chun, Powell, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415113/
https://ncbi.nlm.nih.gov/pubmed/25941561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2015.03.008
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