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Hyperplasia of Interstitial Cells of Cajal in Sprouty Homolog 4 Deficient Mice

Gastrointestinal stromal tumors, which are thought to derive from interstitial cells of Cajal or their precursors, often harbor an oncogenic mutation of the KIT receptor tyrosine kinase. Sprouty homolog 4, a known negative regulator of ERK pathway, has been identified in the interstitial cells of Ca...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Thys, An, Vandenberghe, Pierre, Hague, Perrine, Klein, Ophir D., Erneux, Christophe, Vanderwinden, Jean-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414615/
https://ncbi.nlm.nih.gov/pubmed/25923139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124861
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