Kit K641E oncogene up-regulates Sprouty homolog 4 and Trophoblast glycoprotein in interstitial cells of Cajal in a murine model of gastrointestinal stromal tumours

Gastrointestinal stromal tumours (GIST) are thought to derive from the interstitial cells of Cajal (ICC) or an ICC precursor. Oncogenic mutations of the receptor tyrosine kinase KIT are present in most GIST. KIT K642E was originally identified in sporadic GIST and later found in the germ line of a f...

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Autors principals: Gromova, Petra, Ralea, Sebastian, Lefort, Anne, Libert, Frédérick, Rubin, Brian P, Erneux, Christophe, Vanderwinden, Jean-Marie
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2009
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828865/
https://ncbi.nlm.nih.gov/pubmed/19453770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00768.x
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