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C‐kit Gene Abnormalities in Gastrointestinal Stromal Tumors (Tumors of Interstitial Cells of Cajal)

Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the GI tract, and expresses KIT and CD34 in most cases. Gain‐of‐function mutation of the c‐kit proto‐oncogene has been described, but its significance in GIST has not yet been fully evaluated. Mutation in exon 11 of the c‐...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Sakurai, Shinji, Fukasawa, Tomoki, Chong, Ja‐Mun, Tanaka, Akira, Fukayama, Masashi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926026/
https://ncbi.nlm.nih.gov/pubmed/10665649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1999.tb00715.x
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