Allelic Loss of 14q and 22q, NF2 Mutation, and Genetic Instability Occur Independently of c‐kit Mutation in Gastrointestinal Stromal Tumor

Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract. Since c‐kit mutation occurs only in one‐third of GIST, there might be other molecular mechanisms. Loss of heterozygosity (LOH), microsatellite instability (MSI) and NF2 gene mutation were invest...

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Publicado en:Jpn J Cancer Res
Main Authors: Fukasawa, Tomoki, Chong, Ja‐Mun, Sakurai, Shinji, Koshiishi, Naoki, Ikeno, Rie, Tanaka, Akira, Matsumoto, Yoshiro, Hayashi, Yukiko, Koike, Morio, Fukayama, Masashi
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2000
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926300/
https://ncbi.nlm.nih.gov/pubmed/11123422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00910.x
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