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Combination Proximal Pulmonary Artery Coiling and Distal Embolization Induces Chronic Elevations in Pulmonary Artery Pressure in Swine

Pulmonary hypertension (PH) is associated with aberrant vascular remodeling and right ventricular (RV) dysfunction that contribute to early mortality. Large animal models that recapitulate human PH are essential for mechanistic studies and evaluating novel therapies; however, these models are not re...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Aguero, Jaume, Ishikawa, Kiyotake, Fish, Kenneth M., Hammoudi, Nadjib, Hadri, Lahouaria, Garcia-Alvarez, Ana, Ibanez, Borja, Fuster, Valentin, Hajjar, Roger J., Leopold, Jane A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414513/
https://ncbi.nlm.nih.gov/pubmed/25923775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124526
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