Chloroquine-Enhanced Efficacy of Cisplatin in the Treatment of Hypopharyngeal Carcinoma in Xenograft Mice

Hypopharyngeal squamous cell carcinoma (HSCC) has the worst prognosis among head and neck cancers. Cisplatin (DDP)-based chemotherapy is an important part of multimodal treatments. However, resistance to DDP severely impairs the effectiveness of chemotherapy for HSCC. Chloroquine (CQ) has been repor...

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Udgivet i:PLoS One
Main Authors: Zhao, Xing-guo, Sun, Rui-jie, Yang, Xiao-yan, Liu, Da-yu, Lei, Da-peng, Jin, Tong, Pan, Xin-liang
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414471/
https://ncbi.nlm.nih.gov/pubmed/25923669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126147
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