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The Expression of SIRT1 and DBC1 in Laryngeal and Hypopharyngeal Carcinomas
RATIONALE AND OBJECTIVE: Sirtuin 1 (SIRT1) plays an important role in tumorigenesis and is increased in many human tumors. DBC1 is a negative regulator of SIRT1 via promotion of p53-mediated apoptosis. It is necessary to investigate the expression of SIRT1 and DBC1 in laryngeal and hypopharyngeal sq...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3689713/ https://ncbi.nlm.nih.gov/pubmed/23805287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066975 |
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