Pathological phenotypes and in vivo DNA cleavage by unrestrained activity of a phosphorothioate-based restriction system in Salmonella

Prokaryotes protect their genomes from foreign DNA with a diversity of defense mechanisms, including a widespread restriction-modification (R-M) system involving phosphorothioate (PT) modification of the DNA backbone. Unlike classical R-M systems, highly partial PT-modification of consensus motifs i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Microbiol
Egile Nagusiak: Cao, Bo, Cheng, Qiuxiang, Gu, Chen, Yao, Fen, DeMott, Michael S., Zheng, Xiaoqing, Deng, Zixin, Dedon, Peter C., You, Delin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414249/
https://ncbi.nlm.nih.gov/pubmed/25040300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12692
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