GOT1/AST1 expression status as a prognostic biomarker in pancreatic ductal adenocarcinoma

Prognostication in pancreatic ductal adenocarcinoma (PDAC) remains a challenge. Recently, a link between mutated KRAS and glutamic-oxaloacetic transaminase (GOT1/AST1) has been described as part of the metabolic reprogramming in PDAC. The clinical relevance of this novel metabolic KRAS-GOT1 link has...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Feld, Fenja M, Nagel, Philipp D, Weissinger, Stephanie E, Welke, Claudia, Stenzinger, Albrecht, Möller, Peter, Lennerz, Jochen K
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Clinical Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414208/
https://ncbi.nlm.nih.gov/pubmed/25595905
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