High SIRT1 expression is a negative prognosticator in pancreatic ductal adenocarcinoma

BACKGROUND: Several lines of evidence indicate that Sirt1, a class III histone deacetylase (HDAC) is implicated in the initiation and progression of malignancies and thus gained attraction as druggable target. Since data on the role of Sirt1 in pancreatic ductal adenocarcinoma (PDAC) are sparse, we...

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Detalhes bibliográficos
Main Authors: Stenzinger, Albrecht, Endris, Volker, Klauschen, Frederick, Sinn, Bruno, Lorenz, Katja, Warth, Arne, Goeppert, Benjamin, Ehemann, Volker, Muckenhuber, Alexander, Kamphues, Carsten, Bahra, Marcus, Neuhaus, Peter, Weichert, Wilko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3850795/
https://ncbi.nlm.nih.gov/pubmed/24088390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-450
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