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Allelic Ratio of KRAS Mutations in Pancreatic Cancer
KRAS is not simply mutated or wild type in pancreatic ductal adenocarcinoma (PDAC); actually, it has never been. More than 90% of PDACs carry mutated KRAS alleles; however, the impact on PDAC biology may vary with the tumor-specific allelic ratio and dosage of mutated KRAS.
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| Published in: | Oncologist |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
AlphaMed Press
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4391769/ https://ncbi.nlm.nih.gov/pubmed/25777349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2014-0408 |
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