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Nuclear-encoded cytochrome c oxidase subunit 4 regulates BMI1 expression and determines proliferative capacity of high-grade gliomas

Nuclear-encoded cytochrome c oxidase subunit 4 (COX4) is a key regulatory subunit of mammalian cytochrome c oxidase, and recent studies have demonstrated that COX4 isoform 1 (COX4-1) could have a role in glioma chemoresistance. The Polycomb complex protein BMI1 is a stem cell regulatory gene implica...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Oliva, Claudia R., Markert, Tahireh, Gillespie, G. Yancey, Griguer, Corinne E.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414193/
https://ncbi.nlm.nih.gov/pubmed/25726526
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