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Repositioning chlorpromazine for treating chemoresistant glioma through the inhibition of cytochrome c oxidase bearing the COX4-1 regulatory subunit

Patients with glioblastoma have one of the lowest overall survival rates among patients with cancer. Standard of care for patients with glioblastoma includes temozolomide and radiation therapy, yet 30% of patients do not respond to these treatments and nearly all glioblastoma tumors become resistant...

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Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Oliva, Claudia R., Zhang, Wei, Langford, Cathy, Suto, Mark J., Griguer, Corinne E.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514931/
https://ncbi.nlm.nih.gov/pubmed/28455961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17247
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