A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts

We designed and synthesized two novel nitrobenzoxadiazole (NBD) analogues of the anticancer agent 6-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)hexan-1-ol (NBDHEX). The new compounds, namely MC3165 and MC3181, bear one and two oxygen atoms within the hydroxy-containing alkyl chain at the C4 position...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Oncotarget
मुख्य लेखकों: De Luca, Anastasia, Rotili, Dante, Carpanese, Debora, Lenoci, Alessia, Calderan, Laura, Scimeca, Manuel, Mai, Antonello, Bonanno, Elena, Rosato, Antonio, Geroni, Cristina, Quintieri, Luigi, Caccuri, Anna Maria
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Impact Journals LLC 2015
विषय:
Research Paper
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414177/
https://ncbi.nlm.nih.gov/pubmed/25595904
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