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A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts
We designed and synthesized two novel nitrobenzoxadiazole (NBD) analogues of the anticancer agent 6-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)hexan-1-ol (NBDHEX). The new compounds, namely MC3165 and MC3181, bear one and two oxygen atoms within the hydroxy-containing alkyl chain at the C4 position...
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出版年: | Oncotarget |
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主要な著者: | , , , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
Impact Journals LLC
2015
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4414177/ https://ncbi.nlm.nih.gov/pubmed/25595904 |
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