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Glutathione Transferase (GST)-Activated Prodrugs
Glutathione transferase (formerly GST) catalyzes the inactivation of various electrophile-producing anticancer agents via conjugation to the tripeptide glutathione. Moreover, several data link the overexpression of some GSTs, in particular GSTP1-1, to both natural and acquired resistance to various...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3834953/ https://ncbi.nlm.nih.gov/pubmed/24300447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics5020220 |
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