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Sertraline-induced potentiation of the CYP3A4-dependent neurotoxicity of carbamazepine: An in vitro study
OBJECTIVE: Drug toxicity is a hurdle to drug development and to clinical translation of basic research. Antiepileptic drugs such as carbamazepine (CBZ) and selective serotonin reuptake inhibitors such as sertraline (SRT) are commonly co-prescribed to patients with epilepsy and comorbid depression. B...
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Publicado no: | Epilepsia |
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Principais autores: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4413932/ https://ncbi.nlm.nih.gov/pubmed/25656284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.12923 |
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