Pathophysiological implications of neurovascular P450 in brain disorders

Over the past decades, the significance of cytochrome P450 (CYP) enzymes has expanded beyond their role as peripheral drug metabolizers in the liver and gut. CYP enzymes are also functionally active at the neurovascular interface. CYP expression is modulated by disease states, impacting cellular fun...

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Udgivet i:Drug Discov Today
Main Authors: Ghosh, Chaitali, Hossain, Mohammed, Solanki, Jesal, Dadas, Aaron, Marchi, Nicola, Janigro, Damir
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067181/
https://ncbi.nlm.nih.gov/pubmed/27312874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2016.06.004
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