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Pathophysiological implications of neurovascular P450 in brain disorders

Over the past decades, the significance of cytochrome P450 (CYP) enzymes has expanded beyond their role as peripheral drug metabolizers in the liver and gut. CYP enzymes are also functionally active at the neurovascular interface. CYP expression is modulated by disease states, impacting cellular fun...

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Detalhes bibliográficos
Publicado no:Drug Discov Today
Main Authors: Ghosh, Chaitali, Hossain, Mohammed, Solanki, Jesal, Dadas, Aaron, Marchi, Nicola, Janigro, Damir
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067181/
https://ncbi.nlm.nih.gov/pubmed/27312874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2016.06.004
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