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Pathophysiological implications of neurovascular P450 in brain disorders
Over the past decades, the significance of cytochrome P450 (CYP) enzymes has expanded beyond their role as peripheral drug metabolizers in the liver and gut. CYP enzymes are also functionally active at the neurovascular interface. CYP expression is modulated by disease states, impacting cellular fun...
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Publicado no: | Drug Discov Today |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5067181/ https://ncbi.nlm.nih.gov/pubmed/27312874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2016.06.004 |
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