Neuroprotective role of Nrf2 for retinal ganglion cells in ischemia-reperfusion

Retinal ischemia plays a critical role in multiple vision-threatening diseases and leads to death of retinal neurons, particularly ganglion cells. Oxidative stress plays an important role in this ganglion cell loss. Nrf2 (NF-E2-related factor 2) is a major regulator of the antioxidant response, and...

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Udgivet i:J Neurochem
Main Authors: Xu, Zhenhua, Cho, Hongkwan, Hartsock, Matthew, Mitchell, Katherine L., Gong, Junsong, Wu, Lijuan, Wei, Yanhong, Wang, Shuang, Thimmulappa, Rajesh K., Sporn, Michael B., Biswal, Shyam, Welsbie, Derek S., Duh, Elia J.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413918/
https://ncbi.nlm.nih.gov/pubmed/25683606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13064
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