MicroRNA-93 activates c-Met/PI3K/Akt pathway activity in hepatocellular carcinoma by directly inhibiting PTEN and CDKN1A

To assess the role of microRNAs (miR) in hepatocellular carcinoma (HCC), we performed comprehensive microRNA expression profiling using HCC cell lines and identified miR-93 as a novel target associated with HCC. We further verified miR-93 expression levels in advanced HCC tumors (n=47) by a direct P...

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Vydáno v:Oncotarget
Hlavní autoři: Ohta, Katsuya, Hoshino, Hiromitsu, Wang, Jinhua, Ono, Shigeshi, Iida, Yuuki, Hata, Keisuke, Huang, Sharon K., Colquhoun, Steven, Hoon, Dave S. B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2014
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413648/
https://ncbi.nlm.nih.gov/pubmed/25633810
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