Expression of the potential therapeutic target CXXC5 in primary acute myeloid leukemia cells - high expression is associated with adverse prognosis as well as altered intracellular signaling and transcriptional regulation

The CXXC5 gene encodes a transcriptional activator with a zinc-finger domain, and high expression in human acute myeloid leukemia (AML) cells is associated with adverse prognosis. We now characterized the biological context of CXXC5 expression in primary human AML cells. The global gene expression p...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bruserud, Øystein, Reikvam, Håkon, Fredly, Hanne, Skavland, Jørn, Hagen, Karen-Marie, van Hoang, Tuyen Thy, Brenner, Annette K., Kadi, Amir, Astori, Audrey, Gjertsen, Bjørn Tore, Pendino, Frederic
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413618/
https://ncbi.nlm.nih.gov/pubmed/25605239
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