Cell-autonomous activation of Hedgehog signaling inhibits brown adipose tissue development

Although recent studies have shown that brown adipose tissue (BAT) arises from progenitor cells that also give rise to skeletal muscle, the developmental signals that control the formation of BAT remain largely unknown. Here, we show that brown preadipocytes possess primary cilia and can respond to...

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Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Nosavanh, LaGina, Yu, Da-Hai, Jaehnig, Eric J., Tong, Qiang, Shen, Lanlan, Chen, Miao-Hsueh
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2015
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413261/
https://ncbi.nlm.nih.gov/pubmed/25848030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420978112
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