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Cell-autonomous activation of Hedgehog signaling inhibits brown adipose tissue development

Although recent studies have shown that brown adipose tissue (BAT) arises from progenitor cells that also give rise to skeletal muscle, the developmental signals that control the formation of BAT remain largely unknown. Here, we show that brown preadipocytes possess primary cilia and can respond to...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Nosavanh, LaGina, Yu, Da-Hai, Jaehnig, Eric J., Tong, Qiang, Shen, Lanlan, Chen, Miao-Hsueh
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413261/
https://ncbi.nlm.nih.gov/pubmed/25848030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420978112
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