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Reversible Lineage-Specific Priming of Human Embryonic Stem Cells Can Be Exploited to Optimize the Yield of Differentiated Cells

The clinical use of human embryonic stem cells (hESCs) requires efficient cellular expansion that must be paired with an ability to generate specialized progeny through differentiation. Self-renewal and differentiation are deemed inherent hallmarks of hESCs and a growing body of evidence suggests th...

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Pubblicato in:Stem Cells
Autori principali: Lee, Jung Bok, Graham, Monica, Collins, Tony J, Lee, Jong-Hee, Hong, Seok-Ho, Mcnicol, Amie Jamie, Shapovalova, Zoya, Bhatia, Mickie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413029/
https://ncbi.nlm.nih.gov/pubmed/25639500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1952
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