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Polycomb enables primitive endoderm lineage priming in embryonic stem cells
Mouse embryonic stem cells (ESCs), like the blastocyst from which they are derived, contain precursors of the epiblast (Epi) and primitive endoderm (PrEn) lineages. While transient in vivo, these precursor populations readily interconvert in vitro. We show that altered transcription is the driver of...
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| Veröffentlicht in: | eLife |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5056788/ https://ncbi.nlm.nih.gov/pubmed/27723457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14926 |
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