Immunogenicity and Efficacy of Flagellin-Envelope Fusion Dengue Vaccines in Mice and Monkeys

The envelope (E) protein of flaviviruses includes three domains, EI, EII, and EIII, and is the major protective antigen. Because EIII is rich in type-specific and subcomplex-specific neutralizing epitopes and is easy to express, it is particularly attractive as a recombinant vaccine antigen. VaxInna...

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Bibliografski detalji
Izdano u:Clin Vaccine Immunol
Glavni autori: Liu, Ge, Song, Langzhou, Beasley, David W. C., Putnak, Robert, Parent, Jason, Misczak, John, Li, Hong, Reiserova, Lucia, Liu, Xiangyu, Tian, Haijun, Liu, Wenzhe, Labonte, Darlene, Duan, Lihua, Kim, Youngsun, Travalent, Linda, Wigington, Devin, Weaver, Bruce, Tussey, Lynda
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Vaccines
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412944/
https://ncbi.nlm.nih.gov/pubmed/25761459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00770-14
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