Immunogenicity and Efficacy of Flagellin-Envelope Fusion Dengue Vaccines in Mice and Monkeys

The envelope (E) protein of flaviviruses includes three domains, EI, EII, and EIII, and is the major protective antigen. Because EIII is rich in type-specific and subcomplex-specific neutralizing epitopes and is easy to express, it is particularly attractive as a recombinant vaccine antigen. VaxInna...

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Dettagli Bibliografici
Pubblicato in:Clin Vaccine Immunol
Autori principali: Liu, Ge, Song, Langzhou, Beasley, David W. C., Putnak, Robert, Parent, Jason, Misczak, John, Li, Hong, Reiserova, Lucia, Liu, Xiangyu, Tian, Haijun, Liu, Wenzhe, Labonte, Darlene, Duan, Lihua, Kim, Youngsun, Travalent, Linda, Wigington, Devin, Weaver, Bruce, Tussey, Lynda
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
Soggetti:
Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412944/
https://ncbi.nlm.nih.gov/pubmed/25761459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00770-14
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