Immunogenicity and Efficacy of Flagellin-Envelope Fusion Dengue Vaccines in Mice and Monkeys

The envelope (E) protein of flaviviruses includes three domains, EI, EII, and EIII, and is the major protective antigen. Because EIII is rich in type-specific and subcomplex-specific neutralizing epitopes and is easy to express, it is particularly attractive as a recombinant vaccine antigen. VaxInna...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Clin Vaccine Immunol
Main Authors: Liu, Ge, Song, Langzhou, Beasley, David W. C., Putnak, Robert, Parent, Jason, Misczak, John, Li, Hong, Reiserova, Lucia, Liu, Xiangyu, Tian, Haijun, Liu, Wenzhe, Labonte, Darlene, Duan, Lihua, Kim, Youngsun, Travalent, Linda, Wigington, Devin, Weaver, Bruce, Tussey, Lynda
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Vaccines
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412944/
https://ncbi.nlm.nih.gov/pubmed/25761459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00770-14
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