Immunogenicity and Efficacy of Flagellin-Envelope Fusion Dengue Vaccines in Mice and Monkeys

The envelope (E) protein of flaviviruses includes three domains, EI, EII, and EIII, and is the major protective antigen. Because EIII is rich in type-specific and subcomplex-specific neutralizing epitopes and is easy to express, it is particularly attractive as a recombinant vaccine antigen. VaxInna...

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Detalhes bibliográficos
Publicado no:Clin Vaccine Immunol
Main Authors: Liu, Ge, Song, Langzhou, Beasley, David W. C., Putnak, Robert, Parent, Jason, Misczak, John, Li, Hong, Reiserova, Lucia, Liu, Xiangyu, Tian, Haijun, Liu, Wenzhe, Labonte, Darlene, Duan, Lihua, Kim, Youngsun, Travalent, Linda, Wigington, Devin, Weaver, Bruce, Tussey, Lynda
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412944/
https://ncbi.nlm.nih.gov/pubmed/25761459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00770-14
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