Superior efficacy of a recombinant flagellin:H5N1 HA globular head vaccine is determined by the placement of the globular head within flagellin

Transmission of highly pathogenic avian influenza (HPAI) between birds and humans is an ongoing threat that holds potential for the emergence of a pandemic influenza strain. A major barrier to an effective vaccine against avian influenza has been the generally poor immunopotency of many of the HPAI...

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Hauptverfasser: Song, Langzhou, Zhang, Yi, Yun, Nadezhda E., Poussard, Allison L., Smith, Jeanon N., Smith, Jennifer K., Borisevich, Viktoriya, Linde, Jenna J., Zacks, Michele A., Li, Hong, Kavita, Uma, Reiserova, Lucia, Liu, Xiangyu, Dumuren, Kunmi, Balasubramanian, Bhuvaneswari, Weaver, Bruce, Parent, Jason, Umlauf, Scott, Liu, Ge, Huleatt, Jim, Tussey, Lynda, Paessler, Slobodan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571653/
https://ncbi.nlm.nih.gov/pubmed/19654064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.07.060
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