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Immunogenicity and Efficacy of Flagellin-Envelope Fusion Dengue Vaccines in Mice and Monkeys

The envelope (E) protein of flaviviruses includes three domains, EI, EII, and EIII, and is the major protective antigen. Because EIII is rich in type-specific and subcomplex-specific neutralizing epitopes and is easy to express, it is particularly attractive as a recombinant vaccine antigen. VaxInna...

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Podrobná bibliografie
Vydáno v:Clin Vaccine Immunol
Hlavní autoři: Liu, Ge, Song, Langzhou, Beasley, David W. C., Putnak, Robert, Parent, Jason, Misczak, John, Li, Hong, Reiserova, Lucia, Liu, Xiangyu, Tian, Haijun, Liu, Wenzhe, Labonte, Darlene, Duan, Lihua, Kim, Youngsun, Travalent, Linda, Wigington, Devin, Weaver, Bruce, Tussey, Lynda
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412944/
https://ncbi.nlm.nih.gov/pubmed/25761459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00770-14
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