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Immunogenicity and Efficacy of Flagellin-Envelope Fusion Dengue Vaccines in Mice and Monkeys
The envelope (E) protein of flaviviruses includes three domains, EI, EII, and EIII, and is the major protective antigen. Because EIII is rich in type-specific and subcomplex-specific neutralizing epitopes and is easy to express, it is particularly attractive as a recombinant vaccine antigen. VaxInna...
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Vydáno v: | Clin Vaccine Immunol |
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Hlavní autoři: | , , , , , , , , , , , , , , , , , |
Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
American Society for Microbiology
2015
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4412944/ https://ncbi.nlm.nih.gov/pubmed/25761459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00770-14 |
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