The Functional Interplay Between the t(9;22)-Associated Fusion Proteins BCR/ABL and ABL/BCR in Philadelphia Chromosome-Positive Acute Lymphatic Leukemia

The hallmark of Philadelphia chromosome positive (Ph(+)) leukemia is the BCR/ABL kinase, which is successfully targeted by selective ATP competitors. However, inhibition of BCR/ABL alone is unable to eradicate Ph(+) leukemia. The t(9;22) is a reciprocal translocation which encodes not only for the d...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Rafiei, Anahita, Mian, Afsar Ali, Döring, Claudia, Metodieva, Anna, Oancea, Claudia, Thalheimer, Frederic B., Hansmann, Martin Leo, Ottmann, Oliver Gerhard, Ruthardt, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412790/
https://ncbi.nlm.nih.gov/pubmed/25919613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005144
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados