Reciprocal t(9;22) ABL/BCR Fusion Proteins: Leukemogenic Potential and Effects on B Cell Commitment

BACKGROUND: t(9;22) is a balanced translocation, and the chromosome 22 breakpoints (Philadelphia chromosome – Ph(+)) determine formation of different fusion genes that are associated with either Ph(+) acute lymphatic leukemia (Ph(+) ALL) or chronic myeloid leukemia (CML). The “minor” breakpoint in P...

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Hlavní autoři: Zheng, Xiaomin, Oancea, Claudia, Henschler, Reinhard, Moore, Malcolm A. S., Ruthardt, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764858/
https://ncbi.nlm.nih.gov/pubmed/19876398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007661
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