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Application of a high-resolution melting technique for the rapid detection of partial replacement of HCV-1b by HCV-1a after PEG-IFNα/RBV therapy

A modified method which can be used for the rapid screening of mutations in the protein kinase R-binding domain (PKR-BD) region and the hypervariable region 1 (HVR1) of hepatitis C virus (HCV) is described. This method is based on a high-resolution melting (HRM) technique used for genotyping single...

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Bibliografiske detaljer
Udgivet i:J Appl Genet
Main Authors: Holysz, M., Bialas, K., Migdalski, P., Kmieciak, D., Trzeciak, W. H.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412693/
https://ncbi.nlm.nih.gov/pubmed/25380691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13353-014-0256-3
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