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Intra-adrenal murine TH-MYCN neuroblastoma tumors grow more aggressive and exhibit a distinct tumor microenvironment relative to their subcutaneous equivalents

In around half of the patients with neuroblastoma (NBL), the primary tumor is located in one of the adrenal glands. We have previously reported on a transplantable TH-MYCN model of subcutaneous (SC) growing NBL in C57Bl/6 mice for immunological studies. In this report, we describe an orthotopic TH-M...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Kroesen, Michiel, Brok, Ingrid C., Reijnen, Daphne, van Hout-Kuijer, Maaike A., Zeelenberg, Ingrid S., Den Brok, Martijn H., Hoogerbrugge, Peter M., Adema, Gosse J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412512/
https://ncbi.nlm.nih.gov/pubmed/25687736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-015-1663-y
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