Regulation of MYCN expression in human neuroblastoma cells

BACKGROUND: Amplification of the MYCN gene in neuroblastoma (NB) is associated with a poor prognosis. However, MYCN-amplification does not automatically result in higher expression of MYCN in children with NB. We hypothesized that the discrepancy between MYCN gene expression and prognosis in these c...

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Detalhes bibliográficos
Main Authors: Jacobs, Joannes FM, van Bokhoven, Hans, van Leeuwen, Frank N, Hulsbergen-van de Kaa, Christina A, de Vries, I Jolanda M, Adema, Gosse J, Hoogerbrugge, Peter M, de Brouwer, Arjan PM
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720985/
https://ncbi.nlm.nih.gov/pubmed/19615087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-239
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