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Toll-like receptor signalling on Tregs: to suppress or not to suppress?

To balance self-tolerance and immunity against pathogens or tumours, the immune system depends on both activation mechanisms and down-regulatory mechanisms. Immunologists have long been focusing on activation mechanisms, and a major breakthrough was the identification of the Toll-like receptor (TLR)...

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Detalhes bibliográficos
Main Authors: van Maren, Wendy W C, Jacobs, Joannes F M, de Vries, I Jolanda M, Nierkens, Stefan, Adema, Gosse J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492951/
https://ncbi.nlm.nih.gov/pubmed/18540962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02871.x
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