Multifaceted effects of synthetic TLR2 ligand and Legionella pneumophilia on Treg-mediated suppression of T cell activation

BACKGROUND: Regulatory T cells (Treg) play a crucial role in maintaining immune homeostasis and self-tolerance. The immune suppressive effects of Tregs should however be limited in case effective immunity is required against pathogens or cancer cells. We previously found that the Toll-like receptor...

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Bibliografiske detaljer
Main Authors: van Maren, Wendy WC, Nierkens, Stefan, Toonen, Liza W, Bolscher, Judith M, Sutmuller, Roger PM, Adema, Gosse J
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078900/
https://ncbi.nlm.nih.gov/pubmed/21435210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-12-23
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